http://www.brianmadden.com/blogs/rubenspruijt/archive/2010/11/27/vdi-and-storage-deep-impact.aspx
In a command shell with admin privileges:
wmic partition get BlockSize, StartingOffset, Name, Index
If the number isn’t a multiple of 65536 (64 kB) or 1048576 (1 MB) the partition is unaligned.